What is mesotherapy?

Mesotherapy consists in injecting in multiple points low-dose drugs. These micro-injections are realized in the skin the closest as possible to the lesions thanks to very thin needles. The term “mesotherapy” has as prefix “meso” (like mesoderm, the middle of the three primary germ layers of the embryo, lying between the ectoderm and endoderm) added to the word “therapy”.

A little history

This technique has been developed by Doctor Michel Pistor in 1952. It is based on a simple principle consisting in “injecting little, rarely, in the good spot”. In other words, a drug must follow the shortest way possible. Hence, the solution found was to inject a product directly under the skin in the proximity of the issue that we want to treat. It’s a question of reducing, at the same time, the drugs’ side effects and injected doses. In 1987, mesotherapy was officially recognized by the Académie Nationale de Médecine (National Academy of Medicine). It is taught is universities since 2002 and validated by the Conseil National de l'Ordre des Médecins (National Medical Association) in 2003.


Situated in Toulouse, Doctor Germain’s office is specialized in mesotherapy which is a recognized technique in the field of aesthetic treatments (skin revitalization), of hair loss (scalp revitalization) and of pain treatment (bone, muscles and migraines). Trained in mesotherapy, Doctor Germain is holding an Inter-University Diploma in Mesotherapy obtained at the University of Bordeaux II.

In which cases is the mesotherapy recommended?

Mesotherapy essentially treats:


  •  Osteoarthritis, back and rheumatic pain.
  • Neuralgia, cephalgia and migraines.




  •  Blood flow disorders (heavy legs, varicose vein).



  •  Stress, sleep disorders, anxiety, depression.




  •  Sports trauma: sprain, tendonitis, pulled muscles, straining, contracture, tennis elbow or lateral epicondylitis.



  •  Hair loss (alopecia).
  • Aesthetic conditions: facial aging (see mesolift)




  •  To treat cellulite and localized fatty tissue.


What happens during the session?

The injections are done locally, on or under the skin either manually with a syringe and a needle, either with the help of a medical jet system. They are not painful.

These micro-injections can be intra-epidermal, intradermal superficial or deep between 1 and 13 mm, according to the lesion, to the area and to the effect searched for. The needle size is also adapted (4 mm, 6 mm or 13 mm).


The drugs used are generally local anesthetics, nonsteroidal anti-inflammatory drugs, muscle relaxants, hormones, vitamins, trace elements. These drugs, chosen according to the doctor’s diagnosis, are diluted in Procaine® or in Xylocaine®: local anesthetic that reduces the pain and improves drug diffusion. Cortisone is never used because we are not in the presence of an infiltration.

All mesotherapy products must absolutely have a marketing authorization for legal injections and are sold in pharmacies.


The minimal drug doses used and their targeted delivery increase their action and their efficiency. Treatment efficiency goes from 10 days to a month.

Side effects and contraindications

Side effects are rare: bruises and local redness, allergies. It is the same in what concerns infection risks if the injections are done in good conditions by an experienced doctor.

The kit is sterile and single use only.

Our advice

Mesotherapy is not an alternative medicine. It uses drugs from the traditional pharmacopeia and allopathic medicine as well as homeopathy.


You can find more information about:


  • mesotherapy,
  • mesotherapy for cellulite treatment,
  • mesotherapy for pain relief,
  • mesotherapy for hair loss,
  • mesolift, on the website of the Association de Mésothérapie et Médecine Esthétique (Mesotherapy and Aesthetic Medicine Association).
Mesotherapy in Toulouse by Dr. Germain